09/07/2022
Results
The median duration of surgery was 130 min (range, 35-300 min). The duration of general anesthesia was 165 min (range, 55-370 min). In the first period (air), the median SpO 2 was 96%(range, 84-100%) and the HR was 84 beats/min (range, 56-160 beats/min). During oxygen supplementation, SpO 2 increased to 99%(range, 94-100%; P < 0.0001), and the HR decreased to 81 beats/min (range, 57-125 beats/min; P < 0.0001). In the second period with air, SpO 2 was 96%(range, 84-100%) and the HR was 85 beats/min (range, 60-144 beats/min;Figure 1A and Figure 1B). There was no significant difference in HR (P = 0.49) or SpO 2 (P = 0.45) between the two periods of air treatment. Overall, 73 of 100 patients responded with decreased HRs with oxygen treatment.
Figure adultfriendfinder 1. (A) Heart rate and (B) arterial oxygen saturation (SpO 2 ) after oxygen supplementation or air by random order (medians and quartiles)*P < 0.0001 by the Wilcoxon test (n = 100).
Figure 1. (A) Heart rate and (B) arterial oxygen saturation (SpO 2 ) after oxygen supplementation or air by random order (medians and quartiles)*P < 0.0001 by the Wilcoxon test (n = 100).
(Figure 2A and Figure 2B) show the change in HR during oxygen therapy, Delta HR, in relation to prestudy-control SpO 2 and HRparing Delta HR for the defined subgroups of initial HRs, we found a significant reduction in HR with oxygen in the patients with initial HRs of 110 beats/min or more compared with patients with HRs of 70 beats/min or less (P < 0.006) and in patients with HRs between 71 and 109 (P < 0.02). Furthermore, when we applied the Kruskal-Wallis test, we found a significant overall intergroup difference between patients with HRs of 70 beats/min or less, between 71 and 109 beats/min, and 110 beats/min of more (P = 0.02). The linear regression analysis of initial HR versus Delta HR was significant (r = 0.30, P = 0.002), but the Spearman correlation test was not significant (r ( s )= 0.17, P = 0.09).
Shape dos. Alterations in heart rate (Delta Time) immediately after clean air supplements for defined subgroups off arterial outdoors saturation (SpO 2 ) with heavens (A) and you can heartrate (HR) which have sky (B)(medians and you can quartiles). The latest Kruskal-Wallis sample produced P = 0.12 for the A beneficial and P = 0.02 in the B.
Figure dos. Alterations in heartbeat (Delta Hr) immediately after oxygen supplementation to possess outlined subgroups away from arterial clean air saturation (SpO dos ) that have heavens (A) and you will pulse rate (HR) with sky (B)(medians and you may quartiles). The brand new Kruskal-Wallis attempt produced P = 0.several from inside the An excellent and you can P = 0.02 into the B.
To own mathematical analyses, we used the Spearman relationship decide to try, a beneficial linear regression studies, the latest Wilcoxon closed rank test, brand new Mann-Whitney U shot, therefore the Kruskal-Wallis try remedied to have ties
Patients which have 1st low SpO 2 beliefs got a pattern towards a more obvious loss of Hour having clean air cures, even though this wasn’t significant (P = 0.06 and you will P = 0.12;Profile 2A). Results of the linear regression analysis (P = 0.18) while the relationship shot (P = 0.37) ranging from initial SpO dos and Delta Hr weren’t extreme.
Thirty-four people were examined into the postoperative day 1, 32 to your postoperative go out 2, 19 towards the postoperative day step 3, and you will fourteen for the postoperative big date 4. Zero extreme differences in Hr with heavens otherwise oxygen (P = 0.step 3 and P = 0.4), changes in Hour (P = 0.5), SpO dos having sky or oxygen (P = 0.06 and P = 0.5), otherwise alterations in SpO dos (P = 0.052) have been located anywhere between people learned with the various other postoperative months.